Discover the Herbal Secret to Enhanced Neurological Health

Research Shows Honokiol Supports Cognitive Health and Stress Response - ecoNugenics

With the rise in neurodegenerative conditions like Alzheimer’s and Parkinson’s, more practitioners and health seekers are relying on natural compounds to promote optimal cognitive and neurological function, and healthy stress responses—without unwanted side effects. 

And with the levels of stress we’re facing in today’s world, these solutions couldn’t come at a better time.  

One supplement that’s gaining attention in the area of neurological wellness, is pure honokiol: A powerful extract derived from Magnolia officinalis bark.  

Extensive published research shows pure honokiol offers important benefits to neurological health through its unique bioactivity in the body— including supporting cell regulatory processes and promoting healthy gene expression.  

For optimal stress response, pure honokiol safely promotes relaxation and a healthy mood, through interaction with GABA receptors. 

“The Guardian of Human Lifespan”

One fascinating study using pure honokiol demonstrated that it supports nerve cells during oxidative stress from free radicals.  

Published in the journal, ACS Chemical Neuroscience, researchers reported that honokiol supports against oxidation-induced cell death in PC12 cells (a specific type of nerve cell), by elevating glutathione levels and up-regulating a number of protective proteins. 

Furthermore, the researchers demonstrated that honokiol activates something called the Nrf2 pathway, offering critical antioxidant support. Nrf2 is a powerful protein that lies dormant within cells and is often described as, “The Guardian of Human Lifespan.” When Nrf2 is activated by select agents such as pure honokiol, it acts as a master regulator of antioxidant functions and healthy gene expression. Research also shows that activating Nrf2 can support a healthy stress response—helping us to further understand the broad-spectrum benefits of pure honokiol for relaxation, mood and cognitive health. 



A powerful, versatile extract that provides a broad-spectrum of critical benefits for neurological function, oncology support, and other key areas of health.*

Highest Purity and Potency Honokiol  

ecoNugenics HonoPure contains 98% pure honokiol, extracting using a supercritical CO2 extraction method to produce the highest purity and potency honokiol product available. Pure honokiol crosses the blood-brain barrier and has been extensively researched for its broad-spectrum benefits across key areas of health. This new study adds to the growing body of data demonstrating the efficacy of pure honokiol for supporting cognitive function, relaxation, mood, and neurological health–safely and naturally.* 


Source: Hou Y, et al. ACS Chem Neurosci. 2018 Jul 10.